Organic Acids
Medchemexpress LLC Thymocartin TFA 25mg | 25MG
Thymocartin TFA is the TFA salt form of Thymocartin (HY-105025) Thymocartin TFA inhibits apoptosis of peripheral blood lymphocytes in HIV infected individuals Thymocartin TFA is potential for immunodeficiency diseases research[1 [2
Medchemexpress LLC 6bK TFA | 1774353-12-6 | 99.7% | 871.94 | 25 MG
6bK TFA is a potent and selective insulin degrading enzyme (IDE) inhibitor with an IC50 value of 50 nM. It increases circulating insulin in high-fat-fed mice and enhances glucose tolerance to oral glucose, especially in high-fat-fed mice.
- Potent and selective insulin degrading enzyme (IDE) inhibitor
- IC50 value of 50 nM
- Increases circulating insulin in high-fat-fed mice
- Enhances glucose tolerance to oral glucose
- Suitable for type 2 diabetes research
Medchemexpress LLC Huwentoxin-IV TFA | 526224-73-7 | 4106.78 | 100 UG
Huwentoxin-IV is a potent and selective sodium channel blocker that inhibits neuronal Nav1.7, Nav1.2, Nav1.3, and Nav1.4. It preferentially blocks the peripheral nerve subtype Nav1.7 by binding to neurotoxin receptor site 4. This compound has demonstrated analgesic effects in animal models of inflammatory and neuropathic pain. Its molecular weight is 4106.78, with a chemical formula of C174H278N52O51S6.
- Inhibits Nav1.7 with an IC50 of 26 nM
- Inhibits Nav1.2 with an IC50 of 150 nM
- Inhibits Nav1.3 with an IC50 of 338 nM
- Inhibits Nav1.4 with an IC50 of 400 nM
- Features sequence: Glu-Cys-Leu-Glu-Ile-Phe-Lys-Ala-Cys-Asn-Pro-Ser-Asn-Asp-Gln-Cys-Cys-Lys-Ss-Lys-Leu-Val-Cys-Ser-Arg-Lys-Thr-Trp-Cys-Lys-Tyr-Gln-Ile-NH2
- Includes disulfide bridges: Cys2-Cys17; Cys9-Cys24; Cys16-Cys31
Medchemexpress LLC BIM 23042 trifluoroacetate | 00-00-0 | 96.2% | 1192.45 g/mol (free base) | C63H73N11O9S2.xC2HF3O2 | 5 MG
BIM 23042 TFA is a somatostatin-like octapeptide analogue that functions as a selective antagonist of the neuromedin B receptor (NMB-R/BB1). Supplied as the trifluoroacetate (TFA) salt at high purity, it is intended for research use in receptor pharmacology and related biochemical assays.
- Selective antagonist of neuromedin B receptor (BB1).
- TFA salt form for improved handling and stability.
- High purity suitable for receptor pharmacology and calcium mobilization assays.
- Supplied as a small, lyophilized quantity for laboratory research use.
- Molecular weight and elemental composition available in the product documentation.
Medchemexpress LLC MPSD control peptide (TFA) | 99.8% | 3080.76 (free base) | 1 MG
MPSD TFA (MARCKS-ED TFA) is the TFA salt form of MPSD, a 25-amino acid peptide derived from the myristoylated alanine-rich C-kinase substrate (MARCKS). It functions as a biological probe capable of sensing membrane curvature and recognizing phosphatidylserine, making it useful for studying membrane shape and lipid composition.
- Derived from MARCKS effector domain sequence
- Senses membrane curvature
- Recognizes phosphatidylserine
- Useful for studying membrane shape and lipid composition
- Appears as a white to off-white solid
- High purity (99.8%)
- Molecular weight: 3080.76 (free base)
Medchemexpress LLC CGGRGD TFA | 98.7% | 677.61 | 5 MG
CGGRGD TFA is a derivative of RGD (Arginine-Glycine-Aspartic acid) that includes cysteine at its N-terminal. This product is intended for research applications only and not for human use. It is referenced in publications regarding the functionalization of PCL fibrous membranes with RGD peptide.
- Biological activity: a derivative of RGD with cysteine at its N-terminal
- Purity: 98.66%
- Molecular weight: 677.61
- Formula: C21H34F3N9O11S
- Appearance: solid
- Color: white to off-white
- Sequence: Cys-Gly-Gly-Arg-Gly-Asp
- Sequence shortening: CGGRGD
- Solubility in vitro: soluble in DMSO at 100 mg/mL (147.58 mM); ultrasonic assistance may be needed, and newly opened DMSO is recommended due to hygroscopic impact on solubility
Medchemexpress LLC Maculatin 1.1 TFA | 96.9% | 2145.55 | 500 UG
Maculatin 1.1 TFA is an antimicrobial peptide that exhibits a Minimum Inhibitory Concentration (MIC) of 7 μM against *Staphylococcus aureus*. This peptide functions by perforating the bacterial membrane of *Staphylococcus aureus*, ultimately leading to bacterial death.
- Antimicrobial peptide.
- Effective against *Staphylococcus aureus* with an MIC of 7 μM.
- Works by perforating the bacterial membrane.
Medchemexpress LLC Homoglutathione trifluoroacetate | 435.37 | C13H20F3N3O8S | 25mg
Homoglutathione (TFA) is a biological molecule
Medchemexpress LLC Ebiratide TFA | 99.0% | 996.23 | 5 MG
Ebiratide TFA (HOE-427) is an ACTH 4-9 derivative that acts directly on the central nervous system and shows memory-enhancing effects. It increases acetylcholine (ACh) metabolism in the rat brain. Ebiratide TFA has neuroprotective efficacy in mice models with electroconvulsive shock and Scopolamine-induced memory impairment, demonstrating anti-amnestic efficacy.
- ACTH 4-9 derivative.
- Acts directly on the central nervous system.
- Exhibits memory-enhancing efficacy.
- Enhances acetylcholine (ACh) metabolism in rat brain.
- Exhibits neuroprotective and anti-amnestic efficacy in animal models.
Medchemexpress LLC L-Phenylalaninamide, 4-(methylsulfonyl)-L-2-aminobutanoyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-D-lysyl-N-(8-aminooctyl)- (TFA) | 99.0% | 996.23 (free base) | 25 MG
Ebiratide (HOE-427) TFA is an ACTH 4-9 derivative that acts directly on the central nervous system and exhibits memory-enhancing efficacy. It enhances acetycholine (ACh) metabolism in rat brain.
- ACTH 4-9 derivative
- Acts directly on the central nervous system
- Exhibits memory-enhancing efficacy
- Enhances acetylcholine (ACh) metabolism in rat brain
- Exhibits neuroprotective efficacy in electroconvulsive shock
- Exhibits anti-amnestic efficacy in Scopolamine (HY-N0296)-induced memory impairment in mice model
Medchemexpress LLC Ω-Agatoxin IVA TFA | 99.10% | 5316.27 | 500 UG
ω-Agatoxin IVA TFA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. It inhibits glutamate exocytosis and calcium influx elicited by high potassium (IC50, 30-225 nM) and also blocks the high potassium-induced release of serotonin and norepinephrine. ω-Agatoxin IVA TFA has no effect on L-type or N-type calcium channels.
- Potent, selective P/Q type Ca2+ (Cav2.1) channel blocker
- Inhibits glutamate exocytosis and calcium influx
- Blocks release of serotonin and norepinephrine
- No effect on L-type or N-type calcium channels
- Appearance: Solid
- Color: White to off-white
- For research use only
Medchemexpress LLC RI(dl)-2 TFA | 98.0% | 1 MG
RI(dl)-2 TFA is a potent and selective RAD51-mediated D-loop formation inhibitor.
- Potent and selective RAD51-mediated D-loop formation inhibitor with an IC50 of 11.1 μM.
- Does not influence RAD51 binding to ssDNA.
- Inhibits homologous recombination (HR) activity in human cells (IC50 of 3.0 μM).
Medchemexpress LLC Ile-AMS TFA | 219931-45-0 | MFCD31619268 | 98.6% | 572.52 g/mol | C18H27F3N8O8S | 10 MG
Ile-AMS TFA is the trifluoroacetic acid (TFA) salt of an aminoacyl-sulfamoyl adenosine analogue that inhibits isoleucyl-tRNA synthetase and displays potent antiparasitic activity (P. falciparum ABS IC50 = 1.19 nM). Intended for laboratory research use only.
- Purity 98.55%.
- Molecular weight 572.52 g/mol; chemical formula C18H27F3N8O8S.
- Soluble in water (≈100 mg/mL); ultrasonic assistance may be required.
- Recommended storage: sealed, away from moisture; in solvent -80°C (6 months) or -20°C (1 month).
- Available in small research quantities, including a 10 mg package.
- Used as a tool compound for studies of aminoacyl-tRNA synthetase inhibition and antiparasitic research.
Medchemexpress LLC VMIP-II (1-21) TFA | 5 MG
vMIP-II (1-21) (NT21MP) TFA is an inhibitor of CXCR4. It interacts broadly with CC and CXC chemokine receptors, inhibiting CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM). This product is for research use only and has not been fully validated for medical applications.
- Molecular formula: C108H169N33O27S.xC2HF3O2
- Sequence: Leu-Gly-Ala-Ser-Trp-His-Arg-Pro-Asp-Lys-Cys-Cys-Leu-Gly-Tyr-Gln-Lys-Arg-Pro-Leu-Pro
- Target: CXCR
- Pathway: GPCR/G protein; immunology/inflammation
Medchemexpress LLC M65 TFA | 99.98% | 4823.53 (free base) | 1 MG
M65 TFA is a deleted peptide of maxadilan (61 a.a.) with a deletion of residues between positions 24 and 42. It acts as a specific antagonist of the PACAP type 1 receptor, inhibiting ANP secretion, and can be utilized for relevant research purposes.
- Specific antagonist of the PACAP type 1 receptor.
- Inhibits ANP secretion.
- Suitable for research.
- In vitro activity: M65 (1 μM) completely blocks cAMP accumulation stimulated by 100 nM of VIP and partially inhibits cAMP accumulation stimulated by 1 nM of maxadilan in rat cortical neurons.